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Pathogenicity Islands and the Evolution of Pathogenic Microbes

Kniha Pathogenicity Islands and the Evolution of Pathogenic Microbes J. Hacker
Libristo kód: 07051677
Nakladateľstvo Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, október 2012
It has been known for a number of years that not only pathogenicity islands but also plasmids and ba... Celý popis
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It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

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