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This book will discuss recent developments in several laboratories studying leishmaniasis. Sequencing of the human genome, as well as of the leishmania genome, has led to significant advances in our understanding of host-immune responses against leishmania, and mechanisms of infection-induced pathology, which is responsible for morbidity and mortality. The book will focus on the latest basic research into leishmaniasis, but will also address how advances in understanding can be applied to prevention, control and treatment of what the WHO has classified a neglected tropical disease.