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Guest Editor Dane Nichols, MD, has assembled a panel of experts focusing on Hemodynamic Support in Septic Shock. Topics of this title include: Oxygen Delivery and Consumption - A Macro-Circulatory Perspective; Mean Arterial Pressure - Therapeutic Goals and Pharmacologic Support, Mechanisms; Detection and Potential Management of Microcirculatory Disturbances; Detection of Hypoxia at the Cellular Level; Type A & B Lactic Acidosis - Recognition, Kinetics, and Associated Prognosis; Venous blood gases - What Can They Tell Us About the State of the Circulation; and, Noninvasive Assessment of Cardiac Preload and Performance through CO2 Rebreathing/ETCO2 Monitoring.