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The emergence of multidrug-resistant tuberculosis (MDRTB) threatens TB control programs worldwide. Outbreaks of MDRTB in the United States grabbed the attention of the medical community and the general public, and subsequent surveys have found 'hot spots' of MDRTB in low- and middle-income countries on four continents. §Unlike other textbooks that contain only a single chapter on MDRTB, this book is devoted to the subject. Contributions from experts from multi disciplines provide detailed descriptions, causation, molecular biology, laboratory diagnosis, treatment, prevention, and public health, aspect of this disease. This book provides an authoritative overview of MDRTB and will be a useful reference book for clinicians, scientists and other health personnel involved in the care of TB and MDRTB patients in industrialized and developing countries.