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This exciting new edition examines the causes of debilitating neurological disorders such as Parkinson's disease, CJD, and Huntington's disease, and gives indications of the prospects for therapy based on the understanding of molecular defects involved in these diseases. Looking at each specific neurological disorder in turn, the book outlines the role of metals in human biology, particularly in the brain, and explores tools for testing potential therapeutic strategies. It concludes with an overview of the potential of both chelation and antioxidant therapy, and outlines some perspectives for the future.