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Medication-Related Osteonecrosis of the Jaws
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Osteonecrosis of the jaw is a well-known side-effect of bisphosphonate therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates. It may also be observed in patients with osteoporosis who are being treated with antiresorptive drugs such as bisphosphonates and denosumab, a monoclonal antibody. This textbook provides detailed, up-to-date information on all aspects of osteonecrosis of the jaw related to treatment with bisphosphonates and denosumab.§Clinical features, pathogenesis, treatment options, and preventive measures are all covered in detail. In addition, safe prevention and treatment strategies are explained for patients receiving antiresorptive drugs who require extractions, implant insertions, and other dento-alveolar surgeries. This book will be of major interest for medical and dental students, dentists, and oral and maxillofacial surgeons.§
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