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Thyroid cancer is the most common malignant endocrine tumor and is the seventh most common cancer seen in throughout out the world. The incidence of thyroid cancer has been increasing more rapidly than any other cancer in many of the cancer registries from different parts of the world. Although the majority of thyroid cancers have an indolent biological behaviour, different histological types have a diverse clinical behaviour. Well-differentiated thyroid cancers have an excellent survival, whereas poorly differentiated and anaplastic thyroid cancers have a very poor outcome. This volume of Head and Neck Cancer Clinics addresses advances, controversies and state-of-the-art treatment recommendations of various types of thyroid cancers.