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"Hormones and Signaling" focuses on the mechanism of gene regulation at the cellular level. It also covers the way hormones act to modulate gene regulation and animal development. It includes information on: nuclear receptors, coactivators, and corepressors; membrane receptors, kinases, and phosphorylation on cascades; hormonal regulation of development; calcium channels and neurotransmitters; chromatin, transcription factors, and regulation of gene expression; JAK/STAT pathways; and hormone-regulated development and gene "knock-out".