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Hepcidin, a peptide hormone composed of 25 amino acids. Hepcidin is synthesized mainly in the liver. Iron deficiency anemia (IDA) is common during pregnancy and is associated with higher maternal morbidity and mortality in Gaza strip.Understanding of hepcidin hormone and its role in iron metabolism could lead to new indicators for earlier detection of cases with IDA. the Objective of this study To assess hepcidin status among IDA pregnant women and its relationship with some biochemical variables in Gaza strip. Hepcidin hormone was lower in IDA pregnant women than healthy pregnant women. Thus it is recommended to carry out further studies to evaluate the role of hepcidin in the diagnosis of IDA among different gestational women.