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Drug Design of Zinc-Enzyme Inhibitors

Jazyk AngličtinaAngličtina
Kniha Pevná
Kniha Drug Design of Zinc-Enzyme Inhibitors Claudiu T. Supuran
Libristo kód: 04882604
Nakladateľstvo John Wiley & Sons Inc, júl 2009
The book gives students and young researchers a resource on zinc enzymes, some of which were intensi... Celý popis
? points 693 b
276.26
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The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and translated into model success stories of the pharmaceutical industry. Up-to-date overviews on the major drug targets of the field are presented, showing the structural basis for catalysis, binding of inhibitors and activators, and their clinical applications. Emergent roles of some recently discovered isozymes in cancer, obesity, epilepsy, pain management, and malaria are also introduced, together with the most recent achievements in drug design from both academia and industry.

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