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There is a growing awareness that the realistic assessment of human cancer risk from exposure to carcinogens requires a broad interdisciplinary approach that considers all aspects that bear on carcinogenesis. This is the first book which systematically discusses the multitude of factors that modify and modulate the outcome of exposure to chemical carcinogens. The book focuses on the interactive relationships between these factors. It provides a unique reference source for basic cancer research, cancer prevention measures, and adjuvant therapies.