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Tissue Engineering, just leaving its egg shells behind may well evolve to a major breakthrough in medicine. Progress in material engineering and biology have made it imaginable in short time to replace lost tissue functions and even lost body parts without the artificial and supply problems of transplantation. In a workshop symposium organized by the European Tissue Repair Society in August 1997 leading scientists from engineering, basic sciences and medicine contributed to this book, which specially stresses the importance of matrix materials for tissue reconstruction and wound healing. Starting with skin, an increasing number of groups is rapidly developing substitutes for most tissues which soon will enter clinical practice.