Bacterial Therapy of Cancer

This volume§explores the evolution of bacterial cancer therapy and describes the modern§techniques used in therapy today. The chapters in this book cover a broad range§of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between§tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of§bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to§achieve remote-control of therapeutic gene expression in tumor-targeting§bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to§drug sensitivity by S. typhimurium A1-R. This book concludes with§a chapter on the future potential of bacterial therapy of cancer. Written in§the highly successful Methods in Molecular Biology series format,§chapters include introductions to their respective topics, lists of the§necessary materials and reagents, step-by-step, readily reproducible laboratory§protocols, and tips on troubleshooting and avoiding known pitfalls.§§Thorough§and informative, Bacterial Therapy of Cancer: Methods and Protocols is§a valuable resource for anyone who is interested in cancer and bacterial§therapy.§