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A how-to manual for quantitative analysis of material efficiency and synthesis strategy in chemistry, this book explains quantitative material efficiency and discusses the role of metrics analysis in actualizing the principles of green chemistry. It covers graph theory as it applies to organic synthesis, the simple mathematical analysis of organic synthesis, and how synthesis plants can be ranked in an unbiased way. The author illustrates the concepts with example target plans and classical targets considered milestones in synthetic chemistry from pharmaceuticals, dyestuffs, agrichemicals, insecticides, natural products, and molecules of theoretical interest.