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This textbook introduces students to Six Sigma, a problem solving technique for reducing defects and variation in processes. The author uses DMAIC phases (Define, Measure, Analyze, Improve and Control) and a data-centric approach, leveraging applied statistics with Minitab®. Readers are enabled to solve novel problems where there isn't an apparent root cause or solution identified. The author walks readers through an (imaginary) case study, explaining both the DMAIC approach and how to use Minitab in a practical way. The presentation includes data sets and instructions on how to analyze data in the context of Six Sigma using Minitab.