Single Cell Sequencing and Systems Immunology

The volume will specially focus on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding molecular mechanisms of systems immunology. The present volume will provide readers revealing insights into and share personal experience on the potential application, significance, workflow, comparison, perspective in future, and challenges of single cell sequencing for discovery and development of disease-specific biomarkers, to understand biological function, activation, or dysfunction of single cells or lymphocytes, to explore functional roles and responses of single cells to therapies. It will provide revealing in-depth information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor-function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics science, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, role in the diseases, and future prospects.§§Dr. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China.§