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This book explore the broader applications and recent developments displayed by quinazoline scaffolds in the disease treatment. Since last 3 decades, a special emphasis on potency was given using screening assays to attain lead candidates. An utter need for the innovation of new, selective and capable inhibitors with an enhanced safety and efficacy profile has motivated us to present an striking approach towards design and development of new pharmaceutical agents. With demonstrated biological importance, quinazolines have become a preferred field for many scientists and their efforts are to a certain extent significant in literature. It was valuable to compile a massive amount of research papers/reports on quinazoline derivatives