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The objective of this book is to focus on new strategies of antiarrhythmic drug treatment and to reconsider the basic mechanisms by which antiarrhythmic drugs might suppress or facilitate cardiac arrhythmias. About 30 well-recognised scientists from Europe and the United States have written condensed review articles on the following topics: basic mechanisms of antiarrhythmic drug action, modulation of antiarrhythmic drug action by disease and injury, pharmacological interactions, variability of the arrhythmogenic substrate, and "novel" antiarrhythmic drugs.